Does Ardour work with Bluetooth?
Short version is that if your OS supports it then it should.
The question is does OS X expose bluetooth devices to CoreAudio the same as it does standard interfaces or not. That I don’t know the answer to off hand, but fairly certain I have had one of my students I helped get a pair of bluetooth headphones working with Mixbus at one point so I suspect the answer is yes.
Perhaps check Apple’s Applications > Utilities > Audio/MIDI Setup Utility. If the Bluetooth device is listed there you can use it.
For half-duplex devices you may have to manually create an Aggregate device and ask Ardour to use that.